The purpose of this course is to help students work through the challenge of understanding risk in international political and economic relations. That challenge is both methodological and substantive. Students will have to tackle ‘how’ we understand and ‘what’ we understand at the same time. Along the way, they will have to consider those things we cannot understand or anticipate with any meaningful degree of precision. They will have to deal with the ‘uncertainty’ that lies beyond the boundaries of ‘risk’. The subject matter is open-ended. Virtually every aspect of politics or economics can be cast in terms of risk and uncertainty, no matter whether we look to the future or reflect upon the past. Therefore, the course builds on a thematically structured, case study approach. Each week introduces a new principle that is useful in understanding risk; each week provides cases that illustrate the usefulness of that new principle. Moreover, as our understanding of risk becomes more sophisticated, the cases become more complex. The ultimate goal is to be able to analyze matters of risk and uncertainty as they manifest around decisions taken by leaders in government or business in the real world.